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QuTEM and OHSU Launch Portland Lab to Enhance West Coast TEM Services

QuTEM AB has expanded its presence in the United States by partnering with Oregon Health & Science University’s Multiscale Microscopy Core (MMC) to open a new laboratory in Portland, Oregon. This facility marks the company’s second U.S. satellite laboratory, following the earlier establishment of operations in Boston. The expansion aims to enhance access to specialized transmission electron microscopy (TEM) services for cell and gene therapy developers on the West Coast.

Headquartered in Stockholm, QuTEM AB provides GMP-certified TEM services and nanoparticle quality control analysis, assisting advanced therapy and nanomedicine developers throughout their product development stages. The Portland laboratory will follow the operational model of the Boston site, allowing U.S.-based clients to submit samples domestically, thus avoiding international shipping and reducing transportation-related risks.

The OHSU facility houses a Biosafety Level 2 laboratory capable of handling a variety of samples, including Adeno-Associated Virus (AAV), lentiviral vectors, and lipid nanoparticles. Using QuTEM’s protocols, OHSU scientists will conduct sample preparation and TEM imaging, with the resulting data securely transmitted to QuTEM’s Stockholm headquarters for analysis. The company’s proprietary Gridsee software will be employed to assess critical quality attributes, such as particle morphology and integrity, and to determine capsid content levels for AAV samples.

This collaboration is expected to improve logistics and analytical timelines for biotechnology companies across the West Coast, including those in Seattle, San Francisco, and San Diego. By processing samples domestically, companies can avoid the complications often associated with international shipping, such as temperature fluctuations and customs delays. QuTEM CEO Josefina Nilsson noted that the expansion reflects regional client demand for accessible, high-quality analytical services akin to those available in Boston.

Operating through OHSU’s core service model, QuTEM utilizes MMC’s equipment and expert personnel on a fee-for-service basis while maintaining responsibility for image analysis and quality reporting via its headquarters. This approach ensures consistency across its laboratories through standardized equipment and software. The Portland laboratory is now accepting projects, offering support for research and development and programs moving toward GMP release testing.

About QuTEM
QuTEM AB is a Stockholm-based provider of GMP-certified TEM services and quality control analysis of nanoparticles. It serves biopharmaceutical companies developing AAV, LNP and other viral vector-based therapies. The QuTEM team builds on almost twenty years of hands-on electron microscopy experience. It combines latest-generation instruments with Gridsee, its in-house image analysis software, and validated methods to deliver objective, reproducible data from early research through GMP release. With satellite laboratories in Boston and Portland, QuTEM supports developers in Europe and across the United States.

About the OHSU Multiscale Microscopy Core
The Multiscale Microscopy Core (MMC) at Oregon Health & Science University provides academic and commercial users with access to advanced electron microscopy platforms, together with project consultation, specimen preparation, imaging and analysis services. The core was established in 2013 and is housed in the OHSU’s Robertson Life Sciences Building in Portland, Oregon. Its instruments include a Glacios cryo-transmission electron microscope, a Talos 120C G2 transmission electron microscope, a Helios UC5 Focused Ion Beam scanning electron microscope (FIB-SEM) with cryo capabilities, a Helios G3 FIB-SEM and an Apreo Volume Scope Serial Block face SEM. The MMC is a member of the OHSU University Shared Resource Cores.
Jingyi Zhang
QUTEM AB

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